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5 Defenders®

Our 5 Defenders® formula combines five of the most respected functional mushrooms; Reishi, Shiitake, Maitake, Turkey Tail, and Chaga to help support immune health and overall vitality as part of your daily wellness routine. 

A white bottle labeled "5 Defenders® Organic Mushroom Blend Capsules" by Real Mushrooms, featuring a powerful mushroom complex with 90 capsules for immune support.
A person pours Real Mushrooms 5 Defenders® Organic Mushroom Blend Capsules into another’s hand, with a glass of water and lemons in the background, emphasizing natural immune support.
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A teal and white "Real Mushrooms" package displays 5 Defenders® Organic Mushroom Complex – Bulk Powder, a 45g dietary supplement rich in beta-glucans for immune support.
A hand pours coffee from a moka pot into a brown mug beside a packet of Real Mushrooms 5 Defenders® Organic Mushroom Complex – Bulk Powder and a wooden spoon with powder on a beige countertop.
A brown resealable pouch labeled "Mushroom Hot Chocolate Mix" by Real Mushrooms, featuring organic cacao powder and a vegan mushroom extract blend. Contains 15 servings (240g) and displays the USDA Organic logo.
Someone uses a milk frother to stir a mug of hot chocolate made with Real Mushrooms’ Mushroom Hot Chocolate Mix, beside a bag of the unsweetened mix on the table.
White bottle labeled "Pet Defenders™ Organic Mushroom Blend Capsules for Pets" by Real Mushrooms, an immune support supplement for dogs and cats with 90 veterinarian-formulated capsules featuring organic mushroom extracts.
A bottle of Real Mushrooms Pet Defenders™ Organic Mushroom Blend Capsules for Pets sits on a surface with several capsules, showcasing immune support for pets with organic mushroom extracts.
A brown box labeled "Mushroom Chocolate Bar - 5 Pack" by Real Mushrooms, features USDA organic 75% dark chocolate bars with functional mushrooms—250 mg mushroom extract per serving.
The Mushroom Chocolate Bar - 5 Pack by Real Mushrooms features 75% organic dark chocolate with functional mushrooms, delivering 250 mg mushroom extracts per serving and is USDA organic certified.
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A beige resealable pouch labeled "Functional Coconut Creamer - Powder" by Real Mushrooms features a plant-based mushroom extract blend, USDA organic seal, and a net weight of 6.35 oz (180g).
A coffee machine pours espresso into a white mug next to a spoon and a package of Real Mushrooms Functional Coconut Creamer - Powder on the kitchen counter.

5 Defenders® FAQs

All our mushroom extracts are from the leading supplier of organic mushroom extracts: Nammex. They have over 40 years of mushroom growing experience and were one of the first companies to bring organic functional mushroom extracts to North America.

Their ingredients go through rigorous quality control and are tested twice for heavy metals, agricultural chemicals and microbial contamination to ensure they meet all standards for dietary supplements of this nature. All of their extracts are made from certified organic mushrooms (fruiting bodies), organically grown or wildcrafted from deep within mountain regions of China.

Mushrooms used for dietary supplements are seldom grown in North America since they are too expensive. China is the leading supplier of mushrooms worldwide and supplies over 90% of the world’s mushrooms. 

It has a rich history of mushroom use as both food and medicine and is the birthplace of mushroom cultivation, with shiitake being farmed in the early 1200s. China is one of the only places in the world where you can get 100% organic mushroom (fruiting body) extracts that can be sold at an affordable price.

It is extremely important to distinguish the difference between mushrooms and mycelium.

Mushrooms are the "fruit" and reproductive stage of these organisms, while the mycelium is the root system or "body" of the fungus.

Mushrooms contain much higher levels of active compounds like beta-glucans, and there is a large body of research on them. They have also been consumed for thousands of years as food, and many health benefits have been shown from just mushroom consumption.

Mycelium is commonly grown on a grain substrate, and this grain cannot be separated from the mycelium, so much of the final product is actually grain with no mushrooms present. This shows up in high amounts of starch and low amounts of active compounds like beta-glucans. 

For these reasons, Real Mushrooms only utilizes mushrooms in all of its products, with verified levels of important active compounds like beta-glucans, and is always guarded against starchy fillers like grain.

Choose our mushroom supplement blend to incorporate traditionally valued functional mushrooms into your daily routine, easily. Our extracts are carefully produced to ensure they are rich in beneficial compounds, offering a reliable, effective solution for those looking to integrate these health benefits into their daily routine.

Our organic mushroom extract powders are made with zero fillers, starch, or mycelium fermented grain. They are extracted and third-party tested for the highest potency and purity. These measures ensure you get a high-quality mushroom supplement blend with a full spectrum of easy-to-digest nutrients & active compounds.

What is the proportion of each ingredient in the 5 Defenders® mushroom blend?

5 Defenders® combines the extract powders of 5 mushrooms, consisting of:

  • 30% Turkey Tail Mushroom
  • 20% Reishi Mushroom
  • 20% Shiitake Mushroom
  • 20% Maitake Mushroom
  • 10% Chaga

5 Defenders® combines the extract powders of 5 mushrooms, consisting of:

  • 30% Turkey Tail Mushroom
  • 20% Reishi Mushroom
  • 20% Shiitake Mushroom
  • 20% Maitake Mushroom
  • 10% Chaga

5 Defenders® is a blend of organic mushroom extracts designed to help support overall well-being, resilience, and immune system health.

It is the product that most new customers begin with Real Mushrooms®.

While single-mushroom supplements can be helpful for targeted needs, they often address just one slice of the wellness picture. Real Mushrooms' 5 Defenders® blend, however, supports:

  • Innate and adaptive immune function
  • Oxidative stress resilience
  • Calm, balanced energy
  • Gut and microbiome health (through Turkey Tail's prebiotic-like effects)†

The blend is derived from 100% organic mushrooms, not mycelium fermented grain, so you get potency without compromise: no starch, no fillers, just the active compounds your body can actually use.

5-Time Winner

Best Mushroom Supplement Brand: ConsumerLab.com Survey

Trusted by wellness seekers and professionals alike, our mushroom supplements have earned the rating of Best Mushroom Supplement Products five years in a row by consumers in ConsumerLab.com Annual Supplement Survey.

Gold badge from ConsumerLab.com with text and logo, featuring a red ribbon and black text.

†Ratings based on results of the 2025 ConsumerLab.com Survey of Supplement Users. More information.

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