25 reviews
Pet Defenders™ Organic Mushroom Blend Capsules for Pets
Pet Health†
$29.95
Size
90 Capsules
Quantity
100% Satisfaction • Fast Free Shipping $75+ • Secure Checkout
Comprehensive immune support for pets in every serving.
This veterinarian-formulated blend of five organic mushroom extracts: Turkey Tail, Reishi, Maitake, Shiitake, and Chaga, delivers concentrated beta-glucans and antioxidants to help fortify your pet’s natural defenses.
Convenient and filler-free, 5 Defenders® provides comprehensive, whole-body support to keep your companion strong, resilient, and thriving through every stage of life.
Designed to strengthen the foundation of health, offering daily support for vitality, balance, and longevity.
- Immune System Support
- Whole-Body Vitality and Organ Balance
- Cellular Health Protection for Aging Well
- Gut and Digestive Support
- Resilience Against Environmental Stressors
- Antioxidant Support for Healthy Inflammation Response
- Energy and Endurance Maintenance
Administer 1 capsule for each 20 pounds of body weight once daily or as directed by your veterinarian.
Real Mushrooms products are always:
- Rated the #1 Mushroom brand by ConsumerLab
- Organic mushroom identity authenticated by Purity-IQ™
- Verified for active compounds, safety, & purity through third-party testing
- Free of grains, starches, and fillers
- Sourced from mushroom (fruiting bodies) only—never mycelium fermented grain
- Produced in a Good Manufacturing Practices (GMP)-compliant facility
This is our Real Mushrooms Guarantee: no shortcuts, no gimmicks—just real mushrooms.
Real Pets. Real Results.†
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“It has made a huge difference! His blood counts are much improved! He acts much better, more spark and energy.”†
– Verified Customer
“We see great results in the dogs that need immune support. Both the capsules and powder are readily accepted. Very happy!”†
– Verified Customer
“My vet recommended this product for my puppy who was recovering from parvo. That was a year ago, and today he is a happy healthy dog. I was so impressed with the product that I bought more to give to my family.”†
– Verified Customer
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Real Ingredients
Reishi Mushroom (Organic)
Reishi mushroom is an adaptogenic fungus, treasured for centuries in traditional wellness practices and often called the “mushroom of immortality.”
Multiple ingredients in this powerful mushroom extract provide a healthy response to inflammation and discomfort.
Turkey Tail (Organic)
Turkey Tail is a powerful functional mushroom that grows worldwide and has been used for millennia for its strong immune modulating and health promoting properties that are due to it having the highest amount of beta glucans of any other functional mushroom
Turkey Tail supports a healthy immune response to the many health challenges that affect our pets. Its benefit to the immune system of dogs has been documented in several published studies.
Shiitake (Organic)
Shiitake mushroom is a highly prized and very tasty edible mushroom that has been studied extensively and found to provide a wide variety of powerful benefits to the immune system, digestive system, metabolism, cognition, longevity as a restorative mushroom.
Shitake mushroom’s wide-ranging benefits can improve pet health by the actions of its beta glucans, ergothioneine and eritadenine compounds.
Maitake (Organic)
Maitake mushroom is known for its strong immune modulating benefits that are due to its unique multi-branched soluble beta glucan content. Like Shiitake, Maitake is also a prized edible mushroom, and a treat to find growing wild.
Maitake’s unique beta glucans have a powerful effect improving pet immune function to be able to meet many health challenges. There are several published studies of maitake effects in dogs.
Chaga (Organic)
Chaga is a fungal mycelium that has grown into the birch tree and creates an outgrowth of the bark that looks like the tree has cancer. It has been in use for many years by indigenous people for its many health benefits.
Chaga can support pet immune function, reduce fatigue, support cardiovascular health, enhance liver, stomach and skin health, as well as help to maintain healthy blood sugar levels.
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4-Time Winner
Best Mushroom Supplement Brand: ConsumerLab.com Survey
Trusted by wellness seekers and professionals alike, our mushroom supplements have earned the rating of Best Mushroom Supplement Products four years in a row by consumers in ConsumerLab.com Annual Supplement Survey.
†Ratings based on results of the 2025 ConsumerLab.com Survey of Supplement Users. More information.
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Real Quality
Real Mushrooms is built on 50+ years of mycological and mushroom-growing expertise. Our founder’s roots trace back to the beginning of the functional mushroom category in North America. Today, we continue to lead the industry in science-backed and effective mushroom supplements.
Purity, Potency, Transparency
Every batch of our supplements is lab-verified for purity. We test for unwanted fillers and various contaminants.
We ensure quality along the entire production process:
- Source: Organically grown mushrooms from trusted long-term partners
- Process: Extracted for bioavailability, lab-verified, and blended/packaged in the USA
- Testing: Each batch is tested for heavy metals, microbial contamination, pesticides & solvents
Nothing hidden. No marketing gimmicks. Just real ingredients, real science, and real results.
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Real Vet. Real Formula.
Dr. Robert Silver, DVM, MS
Chief Veterinary Officer Formulator
Dr. Robert Silver brings to the Real Mushrooms Science Team 40 years of practical clinical experience treating small and large animals with diet, acupuncture, nutraceuticals, botanicals, and medicinal mushrooms.
- Graduated from Colorado State's College of Veterinary Medicine in 1982.
- Established one of the first integrative vet clinics in the USA in Boulder, CO in 1993.
- Adjunct faculty member at several veterinary colleges.
- Published papers and books on the topic of alternative medicines for pet health.
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Real Mushrooms vs. Other Brands
Not all mushroom supplements are created equal. Real Mushrooms has set the standard for the most effective mushroom products because we have never compromised on quality. Here’s how Real Mushroom supplements compare with the other leading brands on the market.
| Real Mushrooms | Other Brands | |
|---|---|---|
| Mushroom Source | 100% organic mushrooms (fruiting bodies) | Mycelium fermented grain (starch) and fillers |
| Beta-Glucan Content | Guaranteed beta-glucans — every batch third party tested for identity, purity and potency | Typically low beta-glucans and not disclosed — may list total polysaccharides instead which includes any starches |
| Extraction Method | Hot water extracted or dual extracted for potency & optimal absorption | Improperly extracted or simply dried and ground |
| Filler-Free Guarantee | No starch, no fillers, no mycelium fermented grain | Commonly contains grain (rice, oats or sorghum), starch and/or maltodextrin |
| Transparency | Full disclosure of ingredients, sourcing, testing and extraction | Vague or misleading marketing and unclear labeling |
| Cost per Serving | Cost-effective for active compounds concentration in every serving | Very expensive for amount of active compounds present |
| Expertise | 50+ years of mushroom cultivation expertise — leader in supplement industry quality & standards | Mislead customers with ambiguous labeling and filler-heavy products |
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Take the guesswork out of your mushroom supplement. Start enjoying real results now.
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K
Krista It really helped my dogs immune system! Less scratching & her coat came in full after loosing so much hair after her surgery 🥰🐾
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Barbara L. On the advice of our veterinarian, we purchased 5 Defenders for our elderly Labrador, Buddy. His appetite has improved and his coat has regained its shine! My husband and I take Real Mushrooms Lions Mane daily and we agree with Buddy: Better Living Through Botany!!
J
Jennifer Seems like its really helping my itchy German shepherd!
H
Holly Love this product
K
Kimberly Keeping my pups healthy!!!
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Frequently Asked Questions
All our mushroom extracts are from the leading supplier of organic mushroom extracts: Nammex. They have over 40 years of mushroom growing experience and were one of the first companies to bring organic functional mushroom extracts to North America.
Their ingredients go through rigorous quality control and are tested twice for heavy metals, agricultural chemicals and microbial contamination to ensure they meet all standards for dietary supplements of this nature. All of their extracts are made from certified organic mushrooms (fruiting bodies), organically grown or wildcrafted from deep within mountain regions of China.
Mushrooms used for dietary supplements are seldom grown in North America since they are too expensive. China is the leading supplier of mushrooms worldwide and supplies over 90% of the world’s mushrooms.
It has a rich history of mushroom use as both food and medicine and is the birthplace of mushroom cultivation, with shiitake being farmed in the early 1200s. China is one of the only places in the world where you can get 100% organic mushroom (fruiting body) extracts that can be sold at an affordable price.
It is extremely important to distinguish the difference between mushrooms and mycelium.
Mushrooms are the "fruit" and reproductive stage of these organisms, while the mycelium is the root system or "body" of the fungus.
Mushrooms contain much higher levels of active compounds like beta-glucans, and there is a large body of research on them. They have also been consumed for thousands of years as food, and many health benefits have been shown from just mushroom consumption.
Mycelium is commonly grown on a grain substrate, and this grain cannot be separated from the mycelium, so much of the final product is actually grain with no mushrooms present. This shows up in high amounts of starch and low amounts of active compounds like beta-glucans.
For these reasons, Real Mushrooms® only utilizes mushrooms in all of its products, with verified levels of important active compounds like beta-glucans, and is always guarded against starchy fillers like grain.
NSF certification ensures the product is manufactured under strict cleanliness, safety, and quality control guidelines. This means you can trust that Daily Dawg Powder meets the highest standards for pet supplements.
5 Defenders® combines five functional mushrooms in a synergistic blend that helps support a strong, balanced immune system and promotes overall quality of life.
Our pet capsules contain the same organic mushroom extracts used in our human line, but the main differences are in dosage and size.
Pet capsules contain 300 mg per capsule, compared to 500 mg in the human version. They are also smaller, making them easier for pets to take.
They can be given with or without food. Many pet parents find that administering capsules with meals is easier and helps ensure consistency over time.
Administer 1 capsule for each 20 pounds of body weight once daily or as directed by your veterinarian.
There are several options for giving capsules to your pet. You can open the capsule and sprinkle the powder over their food, or you can hide the whole capsule in a pill pocket or another tasty treat such as cheese, a small amount of butter, or a meatball.
Yes. You can open the capsule and mix the powder into your pet’s food for easier administration.
Natural ingredients do not always flow smoothly through processing equipment, so capsule manufacturers must use small amounts of other ingredients to fill capsules. We work closely with our encapsulation partners to ensure that only what is necessary is included.
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