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Daily Calm Trio

Longevity & Cognition

$86.14
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$114.85
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Stay calm, clear, and resilient throughout your day. The Daily Calm Trio from Real Mushrooms® combines Lion’s Mane CALM, Reishi, and Ergo+ to support a relaxed yet alert state, helping you stay balanced, focused, and steady under pressure. Unlock long-term wellness with this simple daily stack for calm and resilience.

  • Supports a calm, relaxed, yet alert state*
  • Promotes emotional balance and resilience*
  • Helps manage occasional stress*
  • Supports immune health and overall wellness*
  • Supports healthy aging and cellular health*

Take 2 capsules of each daily to support a calm and balanced mindset. They can be taken in the morning or evening, depending on your routine.

Real Mushrooms products are always:

  • Rated the #1 Mushroom brand by ConsumerLab
  • Made from USDA Certified Organic Mushrooms
  • Verified for active compounds, safety, & purity through third-party testing
  • Purity-IQ verified for authenticity using nuclear magnetic resonance
  • Free of grains, starches, and fillers
  • Sourced from mushroom (fruiting bodies) only—never mycelium fermented grain
  • Produced in a Good Manufacturing Practices (GMP)-compliant facility

This is our Real Mushrooms Guarantee: no shortcuts, no gimmicks—just real mushrooms.

100 Days

100 Days

Money-Back Guarantee

94,000+

94,000+

5 star reviews

50+ Years

50+ Years

Growing experience

5-Time Winner

Best Mushroom Supplement Brand: ConsumerLab.com Survey

Trusted by wellness seekers and professionals alike, our mushroom supplements have earned the rating of Best Mushroom Supplement Products five years in a row by consumers in ConsumerLab.com Annual Supplement Survey.

Gold badge from ConsumerLab.com with text and logo, featuring a red ribbon and black text.

†Ratings based on results of the 2025 ConsumerLab.com Survey of Supplement Users. More information.

Real People. Real Results.

★★★★★

"The brain fog from 2 bouts with Covid are in the past. I've been taking a daily boost of Lion's Mane and the fog has lifted. I'm so grateful for this powerful, natural addition to a healthy diet... what a difference it's making!"†

– Verified Customer

★★★★★

“Man I love coffee. But I can only drink one cup before I regret it. Taking Cordyceps gives that extra boost but without feeling terrible… Overall, I find it helps make both mental tasks and weightlifting easier.”†

– Verified Customer

★★★★★

“I have a condition that causes constant fatigue. After taking the Ergo + for a week or so, I started to feel a difference. I have more stamina through the day, and my mind feels clearer.”†

– Verified Customer

Real Science

Real Mushrooms is built on 50+ years of mycological and mushroom growing expertise. Our founder’s roots trace back to the beginning of the functional mushroom category in North America. Today we continue to lead the industry in science-backed and effective mushroom supplements.

Every batch of 5-Defenders is lab-verified for beta-glucan content and free of unwanted fillers like starch or alpha-glucans from grain. This scientific transparency ensures that what’s on the label is exactly what’s in the bottle.

Real Quality

Why Beta-Glucans Matter

Beta-glucans are the primary active compounds in mushrooms that support immune function.† Most mushroom products don’t list beta-glucan content in the Supplement Facts panel, but we do.

Beta-Glucan testing proves that a mushroom supplement is made with actual mushrooms and not diluted with grains or fillers. High levels of Beta-glucans per mushroom species indicate high purity and potency, versus mycelium-fermented grain products that contain high levels of grain starch instead.

Real Mushrooms products offer potency you can trust, in every serving.

We use only 100% mushroom (fruiting body)—no grain, no mycelium, no fillers.

This product has received the Purity-IQ™ Authenticity Certification Program - a cutting-edge nuclear magnetic resonance technique that confirms we use the correct mushroom species and nothing else.

View our certification on Purity-IQ

Certified organic. Verified species identity. No shortcuts. Just clean, potent mushrooms—exactly as nature intended.

We partner with experienced mushroom growers using Di Dao 地道(spiritual homeland) cultivation practices to harvest mushrooms in their geo-authentic environments. Our mushroom extract contains only the real mushroom—grown, extracted, and tested with integrity.

Bar chart showing customer preferences for product attributes with 'Quality' being the highest.

Real Mushrooms vs. Other Brands

Not all mushroom supplements are created equal. Real Mushrooms has set the standard for the most effective mushroom products because we have never compromised on quality. Here’s how Real Mushroom supplements compare with the other leading brands on the market.

Real Mushrooms

100% organic mushrooms

Guaranteed >30% beta-glucans

Hot water extracted or dual extracted

No starch · no fillers

Full disclosure of ingredients, sourcing, testing and extraction

Cost-effective for active compound concentration in every serving

50+ years mushroom cultivation expertise

Other Brands

Mycelium fermented grain (starch + fillers)

Typically low, often undisclosed

Improperly extracted or simply dried and ground

Commonly contains rice, oats or sorghum starch and/or maltodextrin

Vague or misleading marketing and unclear labeling

Very expensive for amount of active compounds actually present

Mislead customers with ambiguous labeling and filler-heavy products

Take the guesswork out of your mushroom supplement.

Start enjoying real results now.

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100% organic mushroom extracts Verified beta-glucans No grain fillers 50 years of experience Wellness backed by 40,000+ customers

This product is ideal for individuals who:

  • Want calm without drowsiness
  • Experience daily cognitive or emotional load
  • Are looking for a non-sedating alternative to traditional calming supplements

It is also particularly relevant for individuals navigating life-stage transitions associated with increased stress, cognitive load, and/or irritability and moodiness.

Lion’s Mane CALM is designed as a daily, long-term support formula:

  • L-theanine supports ongoing calm with continued use
  • Lion’s Mane provides cumulative nervous system support

This makes it suitable as part of a long-term wellness routine, not just occasional use.

Yes. Unlike traditional calming herbs or sleep aids, Lion’s Mane Calm supports calm clarity without causing drowsiness.

No. This product is not a sedative.

It is designed to support calm alertness, similar to how practices like meditation promote relaxation while maintaining awareness.

Choose our Reishi mushroom supplements to incorporate traditionally valued functional mushrooms into your daily routine. Our extracts are carefully produced to ensure they are rich in beneficial compounds, offering a reliable, effective solution for those looking to integrate these health benefits into their daily routine.

Our organic Reishi capsules and extract powders are made with zero fillers, starch, or mycelium fermented grain. They are extracted and third-party tested for the highest potency and purity. These measures ensure you get a high-quality mushroom supplement with a full spectrum of easy-to-digest nutrients & active compounds.

Ergo+ provides a natural source of L-ergothioneine, an amino acid studied for its role in supporting cognitive health and oxidative stress balance.* These benefits make it a standout among certain types of mushroom products on the market today for supporting healthy aging.

Ergothioneine is a sulfur-based amino acid. Amino acids are important compounds that help the body build proteins. Ergothioneine was discovered in 1909 by Charles Tanret, a French pharmacist and chemist.

This compound holds powerful antioxidant potential, helping to protect cells from oxidative damage. Certain mushrooms, including some of our products, are known to contain high levels of ergothioneine naturally.

Tanret was examining the ergot fungus, which had recently been responsible for destroying crops, and he discovered the compound by using a purification process. The amino acid name ergothioneine originates from this fungus. While the ergot fungus may damage crops, the amino acid it contains helps essential functions in the human body.

Reishi mushrooms contain bioactive compounds that have been studied for their potential role in overall wellness and vitality*. This fungus contains over 400 different bioactive compounds, including triterpenoids, polysaccharides, nucleotides, sterols, steroids, fatty acids, proteins, peptides, and trace elements.

They contain hundreds of bioactive compounds, mainly in the form of polysaccharides and triterpenes, that assist the body in numerous ways.

Some of the research-supported benefits of Reishi include:*

  • Supports immune health and resilience
  • Supports mood and emotional well-being
  • Promotes restful sleep and relaxation
  • Supports energy, vitality, and healthy aging
  • Helps maintain general wellness and resilience to stress
  • Promotes cardiovascular and circulatory health
  • Helps maintain healthy blood sugar metabolism
  • Supports liver health 
  • Provides antioxidant support
  • Promotes healthy inflammatory response