Introducing
NEW
Lion's
Mane Blends
Real Mushrooms® Lion’s Mane blends combine 100% organic Lion’s Mane with clinically studied ingredients to support both immediate clarity and long-term brain and nervous system health.
Choose FOCUS for clear, sustained concentration without stimulants, or CALM for relaxed alertness and emotional balance without drowsiness.
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Lion’s Mane Blends FAQs
All our mushroom extracts are from the leading supplier of organic mushroom extracts: Nammex. They have over 40 years of mushroom growing experience and were one of the first companies to bring organic functional mushroom extracts to North America.
Their ingredients go through rigorous quality control and are tested twice for heavy metals, agricultural chemicals and microbial contamination to ensure they meet all standards for dietary supplements of this nature. All of their extracts are made from certified organic mushrooms (fruiting bodies), organically grown or wildcrafted from deep within mountain regions of China.
Mushrooms used for dietary supplements are seldom grown in North America since they are too expensive. China is the leading supplier of mushrooms worldwide and supplies over 90% of the world’s mushrooms.
It has a rich history of mushroom use as both food and medicine and is the birthplace of mushroom cultivation, with shiitake being farmed in the early 1200s. China is one of the only places in the world where you can get 100% organic mushroom (fruiting body) extracts that can be sold at an affordable price.
It is extremely important to distinguish the difference between mushrooms and mycelium.
Mushrooms are the "fruit" and reproductive stage of these organisms, while the mycelium is the root system or "body" of the fungus.
Mushrooms contain much higher levels of active compounds like beta-glucans, and there is a large body of research on them. They have also been consumed for thousands of years as food, and many health benefits have been shown from just mushroom consumption.
Mycelium is commonly grown on a grain substrate, and this grain cannot be separated from the mycelium, so much of the final product is actually grain with no mushrooms present. This shows up in high amounts of starch and low amounts of active compounds like beta-glucans.
For these reasons, Real Mushrooms only utilizes mushrooms in all of its products, with verified levels of important active compounds like beta-glucans, and is always guarded against starchy fillers like grain.
- Lion’s Mane FOCUS: Supports mental clarity, memory, and cognitive performance with Alpha-GPC and Cordyceps
- Lion’s Mane CALM: Supports relaxed alertness and emotional balance with L-theanine and Reishi
Both are non-stimulant daily formulas designed for different needs.
Yes. The added ingredients help support more immediate, noticeable effects:
- Alpha-GPC: Supports neurotransmitter activity linked to focus
- L-theanine: Supports calm mental states and relaxation
Lion’s Mane contributes to long-term support, while these ingredients help bridge the gap to short-term experience.
Yes. Many individuals choose based on their daily needs:
- FOCUS for productivity and mental clarity
- CALM for stress-heavy or high-pressure days
Alternatively, you may choose to take FOCUS in the morning and/or afternoon, and CALM in the evening as part of a wind-down ritual.
Yes. Both blends are free from caffeine and stimulants, supporting mental performance without energy spikes, jitters, or crashes.
Not necessarily.
- Lion’s Mane alone: Foundational, long-term brain, nervous system, and gut support
- Blends: Targeted support for specific daily needs
They serve different roles, and some individuals may choose based on their goals
These blends are designed to support how you want to feel during the day, such as:
- Clear, sustained focus (FOCUS)
- Calm, balanced clarity (CALM)
This is achieved by combining fast-acting ingredients (Alpha-GPC or L-theanine) with long-term foundational support (Lion’s Mane).
Lion’s Mane alone acts as a foundational, long-term brain-supporting nutrient.
Lion’s Mane blends are designed to go further by:
- Adding clinically studied active ingredients
- Supporting both immediate experience and long-term outcomes
- Delivering targeted benefits (focus or calm)
This reflects how formulations are used in clinical practice; not single ingredients, but synergistic combinations.
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4-Time Winner
Best Mushroom Supplement Brand: ConsumerLab.com Survey
Trusted by wellness seekers and professionals alike, our mushroom supplements have earned the rating of Best Mushroom Supplement Products four years in a row by consumers in ConsumerLab.com Annual Supplement Survey.
†Ratings based on results of the 2025 ConsumerLab.com Survey of Supplement Users. More information.
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Mushrooms for Whole Health
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