No reviews
Cognitive, Stress & Longevity Support Bundle
Longevity & Skin†
$105.28
Quantity
100-Day Satisfaction Guarantee • Fast Free Shipping $75+ • Secure Checkout
Support your clients with a complete, targeted approach to cognitive performance and stress balance, featured as part of the Real Mushrooms® NANP Webinar and Exhibit, now through May 15th.
This practitioner-exclusive bundle combines Ergo+ (featuring ergothioneine for cellular antioxidant support) with Lion’s Mane FOCUS and Lion’s Mane CALM, two complementary formulas designed to help support mental clarity, focus, and a balanced mood throughout the day.
Made with 100% organic mushroom extracts and no grains or fillers, this bundle reflects the Real Mushrooms® commitment to quality, transparency, and clinically relevant potency, giving practitioners a simple way to offer well-rounded brain and nervous system support in one protocol.
- Supports mental clarity and focus for daily performance
- Helps promote a balanced mood and stress response
- Supports cognitive function and brain health across the day
- Provides antioxidant support at the cellular level (ergothioneine)
- Made with 100% organic mushroom extracts, no grains or fillers
- Designed for practitioners seeking a simple, complementary protocol
Lion's Mane CALM: Take 2 capsules daily.
Lion's Mane FOCUS: Take 2 capsules daily.
Ergo+: Take 1 capsule daily with or without food.
Real Mushrooms products are always:
- Rated the #1 Mushroom brand by ConsumerLab
- Made from USDA Certified Organic Mushrooms
- Verified for active compounds, safety, & purity through third-party testing
- Purity-IQ verified for authenticity using nuclear magnetic resonance
- Free of grains, starches, and fillers
- Sourced from mushroom (fruiting bodies) only—never mycelium fermented grain
- Produced in a Good Manufacturing Practices (GMP)-compliant facility
This is our Real Mushrooms Guarantee: no shortcuts, no gimmicks—just real mushrooms.
100 Days
100 Days
Money-Back Guarantee
94,000+
94,000+
5 star reviews
50+ Years
50+ Years
Growing experience
of
5-Time Winner
Best Mushroom Supplement Brand: ConsumerLab.com Survey
Trusted by wellness seekers and professionals alike, our mushroom supplements have earned the rating of Best Mushroom Supplement Products five years in a row by consumers in ConsumerLab.com Annual Supplement Survey.
†Ratings based on results of the 2025 ConsumerLab.com Survey of Supplement Users. More information.
of
Real People. Real Results.†
★★★★★
"I love mushrooms and they are packed with vitamins that are good for your body. I was happy to find Lions Mane. I find I am much more alert since taking it and it makes me feel good that I am taking something that I know is good for me."†
– Verified Customer
★★★★★
“I have a condition that causes constant fatigue. After taking the Ergo + for a week or so, I started to feel a difference. I have more stamina through the day, and my mind feels clearer.”†
– Verified Customer
★★★★★
"I love mushrooms and they are packed with vitamins that are good for your body. I was happy to find Lions Mane. I find I am much more alert since taking it and it makes me feel good that I am taking something that I know is good for me."†
– Verified Customer
of
Real Science
Real Mushrooms is built on 50+ years of mycological and mushroom growing expertise. Our founder’s roots trace back to the beginning of the functional mushroom category in North America. Today we continue to lead the industry in science-backed and effective mushroom supplements.
Every batch of 5-Defenders is lab-verified for beta-glucan content and free of unwanted fillers like starch or alpha-glucans from grain. This scientific transparency ensures that what’s on the label is exactly what’s in the bottle.
of
Real Quality
Why Beta-Glucans Matter
Beta-glucans are the primary active compounds in mushrooms that support immune function.† Most mushroom products don’t list beta-glucan content in the Supplement Facts panel, but we do.
Beta-Glucan testing proves that a mushroom supplement is made with actual mushrooms and not diluted with grains or fillers. High levels of Beta-glucans per mushroom species indicate high purity and potency, versus mycelium-fermented grain products that contain high levels of grain starch instead.
Real Mushrooms products offer potency you can trust, in every serving.
We use only 100% mushroom (fruiting body)—no grain, no mycelium, no fillers.
This product has received the Purity-IQ™ Authenticity Certification Program - a cutting-edge nuclear magnetic resonance technique that confirms we use the correct mushroom species and nothing else.
View our certification on Purity-IQ
Certified organic. Verified species identity. No shortcuts. Just clean, potent mushrooms—exactly as nature intended.
We partner with experienced mushroom growers using Di Dao 地道(spiritual homeland) cultivation practices to harvest mushrooms in their geo-authentic environments. Our mushroom extract contains only the real mushroom—grown, extracted, and tested with integrity.
of
Real Mushrooms vs. Other Brands
Not all mushroom supplements are created equal. Real Mushrooms has set the standard for the most effective mushroom products because we have never compromised on quality. Here’s how Real Mushroom supplements compare with the other leading brands on the market.
Real Mushrooms
100% organic mushrooms
Guaranteed >30% beta-glucans
Hot water extracted or dual extracted
No starch · no fillers
Full disclosure of ingredients, sourcing, testing and extraction
Cost-effective for active compound concentration in every serving
50+ years mushroom cultivation expertise
Other Brands
Mycelium fermented grain (starch + fillers)
Typically low, often undisclosed
Improperly extracted or simply dried and ground
Commonly contains rice, oats or sorghum starch and/or maltodextrin
Vague or misleading marketing and unclear labeling
Very expensive for amount of active compounds actually present
Mislead customers with ambiguous labeling and filler-heavy products
of
Take the guesswork out of your mushroom supplement.
Start enjoying real results now.
of
100% organic mushroom extracts
•
Verified beta-glucans
•
No grain fillers
•
50 years of experience
•
Wellness backed by 40,000+ customers
•
of
of
of
Lion’s Mane FOCUS may be ideal for individuals who:
- Want noticeable support for focus and clarity
- Experience daily cognitive demand or mental fatigue
- Prefer a non-stimulant alternative to caffeine
It is also particularly relevant for individuals navigating life-stage transitions associated with increased stress or cognitive load.
This product is ideal for individuals who:
- Want calm without drowsiness
- Experience daily cognitive or emotional load
- Are looking for a non-sedating alternative to traditional calming supplements
It is also particularly relevant for individuals navigating life-stage transitions associated with increased stress, cognitive load, and/or irritability and moodiness.
- Lion’s Mane FOCUS: Supports mental clarity, memory, and cognitive performance with Alpha-GPC and Cordyceps
- Lion’s Mane CALM: Supports relaxed alertness and emotional balance with L-theanine and Reishi
Both are non-stimulant daily formulas designed for different needs.
Yes. Many individuals choose based on their daily needs:
- FOCUS for productivity and mental clarity
- CALM for stress-heavy or high-pressure days
Alternatively, you may choose to take FOCUS in the morning and/or afternoon, and CALM in the evening as part of a wind-down ritual.
Ergo+ provides a natural source of L-ergothioneine, an amino acid studied for its role in supporting cognitive health and oxidative stress balance.* These benefits make it a standout among certain types of mushroom products on the market today for supporting healthy aging.
Ergothioneine is a sulfur-based amino acid. Amino acids are important compounds that help the body build proteins. Ergothioneine was discovered in 1909 by Charles Tanret, a French pharmacist and chemist.
This compound holds powerful antioxidant potential, helping to protect cells from oxidative damage. Certain mushrooms, including some of our products, are known to contain high levels of ergothioneine naturally.
Tanret was examining the ergot fungus, which had recently been responsible for destroying crops, and he discovered the compound by using a purification process. The amino acid name ergothioneine originates from this fungus. While the ergot fungus may damage crops, the amino acid it contains helps essential functions in the human body.
of
of