Skip to content
Search
Log in
Pickup options
Three bottles of Real Mushrooms’ The Big 3 supplements are arranged side by side on a plain surface with a neutral background, highlighting their mushroom extracts for brain health and immune support.

The Big 3

Three bottles of Real Mushrooms’ The Big 3 supplements are arranged side by side on a plain surface with a neutral background, highlighting their mushroom extracts for brain health and immune support.
Someone pours Real Mushrooms Organic Cordyceps Extract Capsules from the bottle into their hand, with a glass of water on a wooden table nearby, ready to support natural energy.
A person pours Real Mushrooms Organic Lion's Mane Extract Capsules from a bottle into their hand beside a glass of water on a wooden table, showcasing immune support benefits from organic mushroom extracts.
A person pours 5 Defenders® Organic Mushroom Blend Capsules by Real Mushrooms into their hand, showing immune support, with a glass of water on a wooden table nearby.
White text on brown shows a verified five-star review for Real Mushrooms Organic Cordyceps Extract Capsules, praising increased stamina, energy, and well-being. A small tree logo is displayed at the bottom.
A five-star review says: "Already noticing less mental fogginess, increased focus and stamina with these Organic Lion's Mane Extract Capsules from Real Mushrooms... So grateful for this trusted, clean source!" Logo at the bottom.
A five-star review praises Real Mushrooms 5 Defenders® Organic Mushroom Blend Capsules for boosting immune support for the whole family, including a 4-year-old, with verified customer attribution and tree logo shown.
Comparison chart highlights how Real Mushrooms' RealRest (Reishi, Valerian, Lemon Balm) compares to other brands in source, testing, extraction methods, transparency, and cost per active compound such as Reishi.
A Purity-IQ Certified Authentic badge with QR code and text explains the identity, purity, and consistency verification for Real Mushrooms' Vitamin D from Organic Mushrooms supplement.
Two men kneel inside a greenhouse filled with rows of cultivated Reishi mushrooms. Above them, text reads: "Real Mushrooms: Over 50 Years of Growing Experience. Featuring RealRest—Reishi, Valerian, and Lemon Balm.

The Big 3

  • Energy
†
$76.90 Item is on sale. Compare at $109.85 Bundle • Save 30%

100% Satisfaction • Fast Free Shipping $75+ • Secure Checkout

Three of our best-selling mushroom extracts. One powerhouse bundle.

Expertly crafted to be your all-in-one foundation for brain health, natural energy, and immune function. Together, The Big 3 form a daily ritual rooted in purity and performance. Give your mind and body the well-rounded support they need to feel balanced and resilient.

Whether you’re new to functional mushrooms or looking to simplify your wellness stack, this bundle offers a clean, natural approach to long-term vitality and everyday well-being.

What’s included:



  • Organic Lion’s Mane Extract 120 Capsules x1
    5 Defenders® Organic Mushroom Blend 90 Capsules x1
    Organic Cordyceps Extract 120 Capsules x1

Perfect for:



  • The everyday wellness seeker prioritizing effortless impact
    Individuals looking to maintain both physical energy and mental clarity throughout the day
    First-time mushroom users exploring premium, well-rounded extracts

  • Supports cognitive performance and focus
  • Helps maintain immune health and seasonal wellness
  • Supports stamina, vitality, and natural energy production

Take 2 capsules of each product daily or as recommended by your healthcare provider. Products may be taken together or spread throughout the day based on your routine.

Real Mushrooms products are always:

  • Rated the #1 Mushroom brand by ConsumerLab
  • Made from USDA Certified Organic Mushrooms
  • Verified for active compounds, safety, & purity through third-party testing
  • Purity-IQ verified for authenticity using nuclear magnetic resonance
  • Free of grains, starches, and fillers
  • Sourced from mushroom (fruiting bodies) only—never mycelium fermented grain
  • Produced in a Good Manufacturing Practices (GMP)-compliant facility

This is our Real Mushrooms Guarantee: no shortcuts, no gimmicks—just real mushrooms.
4-Time Winner
Best Mushroom Supplement Brand: ConsumerLab.com Survey

Trusted by wellness seekers and professionals alike, our mushroom supplements have earned the rating of Best Mushroom Supplement Products four years in a row by consumers in ConsumerLab.com Annual Supplement Survey.

Gold ConsumerLab.com badge stating "#1 Top Rated Among Mushroom Products," with "4 Time Winner" and "Real Mushrooms 2025" on a red ribbon.

†Ratings based on results of the 2025 ConsumerLab.com Survey of Supplement Users. More information.
Real People. Real Results.†

"I’m now on my second order of the Lion’s Mane Mushroom Powder. I was strong dislike for anything mushroom on this blends well with my coffee every morning, so this gets 10/10 from me 👍"

-Verified Customer

"Every morning I start off with 5 Defenders as breakfast with my coffee. I love this product, have been taking it for longer than a year and fully believe it's helping. Thanks!

"I've only been using these for one day and I'm already feeling some positive effects. Can't wait to see what it's like once they've had time to fully start working."

-Verified Customer
Real Science

Real Mushrooms is built on 50+ years of mycological and mushroom growing expertise. Our founder’s roots trace back to the beginning of the functional mushroom category in North America. Today we continue to lead the industry in science-backed and effective mushroom supplements.

Every batch of is lab-verified for beta-glucan content and free of unwanted fillers like starch or alpha-glucans from grain. This scientific transparency ensures that what’s on the label is exactly what’s in the bottle.
Real Quality

Why Beta-Glucans Matter

Beta-glucans are the primary active compounds in mushrooms that support immune function.* Most mushroom products don’t list beta-glucan content, but we do.

Beta-Glucans indicate an authentic mushroom product versus myceliated grain products that contain high levels of starch (Alpha-Glucans) instead.

Real Mushrooms offer potency you can trust, in every capsule.

We use only 100% mushroom (fruiting body)—no grain, no mycelium, no fillers.

This product has received the Purity-IQ™ Verified Mushroom Identity Certification—a cutting-edge genomic testing standard that confirms we use the correct mushroom species and nothing else.

View our certification on Purity-IQ

Certified organic. Verified species identity. No shortcuts. Just clean, potent mushrooms—exactly as nature intended.

We partner with experienced mushroom growers using Di Dao 地道(spiritual homeland) cultivation practices to harvest mushrooms in their geo-authentic environments. Our mushroom extract contains only the real mushroom—grown, extracted, and tested with integrity.
Bar chart showing customer preferences for product attributes with 'Quality' being the highest.
Real Mushrooms vs. Other Brands

Not all mushroom supplements are created equal. Real Mushrooms has set the standard for the most effective mushroom products because we have never compromised on quality. Here’s how Real Mushroom supplements compare with the other leading brands on the market.

Real Mushrooms Other Brands
Mushroom Source 100% organic mushrooms (fruiting bodies) Mycelium fermented grain (starch) and fillers
Beta-Glucan Content Guaranteed beta-glucans — every batch third party tested for identity, purity and potency Typically low beta-glucans and not disclosed — may list total polysaccharides instead which includes any starches
Extraction Method Hot water extracted or dual extracted for potency & optimal absorption Improperly extracted or simply dried and ground
Filler-Free Guarantee No starch, no fillers, no mycelium fermented grain Commonly contains grain (rice, oats or sorghum), starch and/or maltodextrin
Transparency Full disclosure of ingredients, sourcing, testing and extraction Vague or misleading marketing and unclear labeling
Cost per Serving Cost-effective for active compounds concentration in every serving Very expensive for amount of active compounds present
Expertise 50+ years of mushroom cultivation expertise — leader in supplement industry quality & standards Mislead customers with ambiguous labeling and filler-heavy products

Take the guesswork out of your mushroom supplement. Start enjoying real results now.

Buy Now
100% organic mushroom extracts
•
Verified beta-glucans
•
No grain fillers
•
50 years of experience
•
Wellness backed by 40,000+ customers
•
Frequently Asked Questions

5 Defenders™ is a blend of organic mushroom extracts designed to help support overall well-being, resilience, and immune system health.

It is the product that most new customers begin with Real Mushrooms.

While single-mushroom supplements can be helpful for targeted needs, they often address just one slice of the wellness picture. Real Mushrooms' 5 Defenders™ blend, however, supports:

  • Innate and adaptive immune function†
  • Oxidative stress resilience†
  • Calm, balanced energy†
  • Gut and microbiome health (through Turkey Tail's prebiotic-like effects)†

The blend is derived from 100% organic mushrooms, not mycelium fermented grain, so you get potency without compromise: no starch, no fillers, just the active compounds your body can actually use.

Choose our Lion’s Mane mushroom supplements to incorporate traditionally valued functional mushrooms into your daily routine. Our extracts are carefully produced to ensure they are rich in beneficial compounds, offering a reliable, effective solution for those looking to integrate these health benefits into their daily routine.

Our organic Lion’s Mane capsules and extract powders are made with zero fillers, starch, or mycelium fermented grain. They are extracted and third-party tested for the highest potency and purity. These measures ensure you get a high-quality mushroom supplement with a full spectrum of easy-to-digest nutrients & active compounds.

Choose our Cordyceps mushroom supplements to incorporate traditionally valued functional mushrooms into your daily routine. Our extracts are carefully produced to ensure they are rich in beneficial compounds, offering a reliable, effective solution for those looking to integrate these health benefits into their daily routine.

Our organic Cordyceps capsules and extract powders are made with zero fillers, starch, or mycelium fermented grain. They are extracted and third-party tested for the highest potency and purity. These measures ensure you get a high-quality mushroom supplement with a full spectrum of easy-to-digest nutrients & active compounds.

The products are identical. The only difference is how you want to consume them.

2 capsules is equivalent to roughly a 1/2 tsp of the mushroom powders.

In terms of potency and efficacy, both the capsules and powders are equally effective at delivering.

The capsules are great for travel, whereas the powder can be added to recipes or mixed in coffee, tea or bone broth.