Mushroom D2Z
Immunity†
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This is more than a vitamin-and-mineral combo. It’s a bioavailable nutrient stack enhanced by functional mushrooms that work in harmony with your immune system and optimize your body’s “rest and recovery” systems. The result? A smarter kind of support for people who want to stay well, feel strong, and wake up refreshed, ready to thrive all year long.
This mushroom-based vitamin D2 and Zinc blend supports your immune system and also optimizes the body systems that regulate rest and recovery.
Every serving (2 capsules) features:
- 30mg of Chelated Zinc for healthy skin, bone, and immunity. Studies have also linked zinc status to better sleep quality and duration.
- 2000 IU of Vitamin D2 from Agaricus Bisporus mushroom (white button mushrooms) for innate immunity regulation, increased calcium absorption, and bone and teeth health maintenance.
- More than 20% beta-glucans from Reishi mushrooms and Chaga that balance and promote healthy immune system function. Also, reishi is gently relaxing and can help calm the nervous system.
By harnessing the power of UV-exposed Agaricus Bisporus mushrooms (white button mushrooms), we provide a vegan-friendly, bioavailable form of vitamin D2 that your body can efficiently utilize.
Take 1 capsule daily with or without food, or as recommended by your healthcare professional.
Pair with other immune-supporting Real Mushroom products such as 5 Defenders or Turkey Tail in times when your body needs the most support.
Real Mushrooms products are always:
- Rated the #1 Mushroom brand by ConsumerLab
- Made from USDA Certified Organic Mushrooms
- Verified for active compounds, safety, & purity through third-party testing
- Purity-IQ verified for authenticity using nuclear magnetic resonance
- Free of grains, starches, and fillers
- Sourced from mushroom (fruiting bodies) only—never mycelium fermented grain
- Produced in a Good Manufacturing Practices (GMP)-compliant facility
This is our Real Mushrooms Guarantee: no shortcuts, no gimmicks—just real mushrooms.
Real Ingredients
Balance Immune Response†
Each serving of D2Z delivers a synergistic blend of vitamins, minerals, and mushroom extracts designed to support your immune system, help your body absorb nutrients more effectively, and promote overall wellness, naturally.
Real Mushrooms, Not Filler
Most mushroom supplements fail because they’re made without mushrooms: they use mycelium fermented grain. Those products have few beneficial fungal compounds—they’re mostly starch.
We use 100% hot water-extracted mushrooms (fruiting body) to unlock the true full spectrum of beneficial compounds.
Highest-Quality, Organic Ingredients
We partner with experienced mushroom growers using Di Dao 地道 (spiritual homeland) cultivation practices to harvest mushrooms in their geo-authentic environments. This supplement contains only real mushrooms, grown, extracted, and tested with integrity.
Best Mushroom Supplement Brand: ConsumerLab.com Survey
Trusted by wellness seekers and professionals alike, our mushroom supplements have earned the rating of Best Mushroom Supplement Products four years in a row by consumers in ConsumerLab.com Annual Supplement Survey.
†Ratings based on results of the 2025 ConsumerLab.com Survey of Supplement Users. More information.
Real People. Real Results.†
★★★★★
“I've been using D2Z for two months and it has helped immensely with my sleep. Before using the capsules I would wake after falling asleep and then have a difficult time falling back to sleep. The D2Z has provided me with a restful sleep without interruptions.”†
– Verified Customer
★★★★★
“Helped boost my immune system, has kept me healthy thru the flu and cold season!”†
– Verified Customer
★★★★★
“I found out by accident that this formula relaxes me and gives me deeper sleep. I didn't buy it for that purpose but I'm going to use it as part of my bedtime routine from now on, it's gentle but makes a noticeable difference.”†
– Verified Customer
Real Science
Real Mushrooms is built on 50+ years of mycological and mushroom growing expertise. Our founder’s roots trace back to the beginning of the functional mushroom category in North America. Today we continue to lead the industry in science-backed and effective mushroom supplements.
Every batch of 5-Defenders is lab-verified for beta-glucan content and free of unwanted fillers like starch or alpha-glucans from grain. This scientific transparency ensures that what’s on the label is exactly what’s in the bottle.
Real Quality
Why Beta-Glucans Matter
Beta-glucans are the primary active compounds in Mushroom D2Z mushrooms that support immune function.* Most mushroom products don’t list beta-glucan content, but we do.
Beta-Glucans indicate an authentic mushroom product versus myceliated grain products that contain high levels of starch (Alpha-Glucans) instead.
Real Mushrooms offer potency you can trust, in every capsule.
We use only 100% mushroom (fruiting body)—no grain, no mycelium, no fillers.
This product has received the Purity-IQ™ Authenticity Certification Program - a cutting-edge nuclear magnetic resonance technique that confirms we use the correct mushroom species and nothing else.
View our certification on Purity-IQ
Certified organic. Verified species identity. No shortcuts. Just clean, potent mushrooms—exactly as nature intended.
We partner with experienced mushroom growers using Di Dao 地道(spiritual homeland) cultivation practices to harvest mushrooms in their geo-authentic environments. Our mushroom Mushroom D2Z extract contains only the real mushroom—grown, extracted, and tested with integrity.
Real Mushrooms vs. Other Brands
Not all mushroom supplements are created equal. Real Mushrooms has set the standard for the most effective mushroom products because we have never compromised on quality. Here’s how Real Mushroom supplements compare with the other leading brands on the market.
| Real Mushrooms | Other Brands | |
|---|---|---|
| Mushroom Source | 100% organic mushrooms (fruiting bodies) | Mycelium fermented grain (starch) and fillers |
| Beta-Glucan Content | Guaranteed beta-glucans — every batch third party tested for identity, purity and potency | Typically low beta-glucans and not disclosed — may list total polysaccharides instead which includes any starches |
| Extraction Method | Hot water extracted or dual extracted for potency & optimal absorption | Improperly extracted or simply dried and ground |
| Filler-Free Guarantee | No starch, no fillers, no mycelium fermented grain | Commonly contains grain (rice, oats or sorghum), starch and/or maltodextrin |
| Transparency | Full disclosure of ingredients, sourcing, testing and extraction | Vague or misleading marketing and unclear labeling |
| Cost per Serving | Cost-effective for active compounds concentration in every serving | Very expensive for amount of active compounds present |
| Expertise | 50+ years of mushroom cultivation expertise — leader in supplement industry quality & standards | Mislead customers with ambiguous labeling and filler-heavy products |
Take the guesswork out of your mushroom supplement.
Start enjoying real results now.
i absolutely love these real mushroom extracts!! without any fillers i see much better results than with other brands
Keeps me sleeping even when I don’t feel like sleeping!
I believe through the process of time this product will show a manifestation of its intent,that's why I purchased it.
Love my Real mushroom supplements thanks again for a great product!
This is a great source of vitamin D
Frequently Asked Questions
All our mushroom extracts are from the leading supplier of organic mushroom extracts: Nammex. They have over 40 years of mushroom growing experience and were one of the first companies to bring organic functional mushroom extracts to North America.
Their ingredients go through rigorous quality control and are tested twice for heavy metals, agricultural chemicals and microbial contamination to ensure they meet all standards for dietary supplements of this nature. All of their extracts are made from certified organic mushrooms (fruiting bodies), organically grown or wildcrafted from deep within mountain regions of China.
Mushrooms used for dietary supplements are seldom grown in North America since they are too expensive. China is the leading supplier of mushrooms worldwide and supplies over 90% of the world’s mushrooms.
It has a rich history of mushroom use as both food and medicine and is the birthplace of mushroom cultivation, with shiitake being farmed in the early 1200s. China is one of the only places in the world where you can get 100% organic mushroom (fruiting body) extracts that can be sold at an affordable price.
The products are identical. The only difference is how you want to consume them.
2 capsules is equivalent to roughly a 1/2 tsp of the mushroom powders.
In terms of potency and efficacy, both the capsules and powders are equally effective at delivering.
The capsules are great for travel, whereas the powder can be added to recipes or mixed in coffee, tea or bone broth.
It is extremely important to distinguish the difference between mushrooms and mycelium.
Mushrooms are the "fruit" and reproductive stage of these organisms, while the mycelium is the root system or "body" of the fungus.
Mushrooms contain much higher levels of active compounds like beta-glucans, and there is a large body of research on them. They have also been consumed for thousands of years as food, and many health benefits have been shown from just mushroom consumption.
Mycelium is commonly grown on a grain substrate, and this grain cannot be separated from the mycelium, so much of the final product is actually grain with no mushrooms present. This shows up in high amounts of starch and low amounts of active compounds like beta-glucans.
For these reasons, Real Mushrooms® only utilizes mushrooms in all of its products, with verified levels of important active compounds like beta-glucans, and is always guarded against starchy fillers like grain.
There has been some debate on whether vitamin D3 is more effective than D2. The two forms have traditionally been regarded as equivalent based on their ability to cure rickets (a skeletal disorder that is caused by a lack of vitamin D, calcium, or phosphate). Most steps involved in the metabolism and actions of vitamin D2 and vitamin D3 are identical. Both forms can raise serum 25(OH)D levels.
Human kidneys may be able to convert Vitamin D2 to the active form of Vitamin D.
Our Vitamin D2 supplement is derived from mushrooms, providing a plant-based alternative for those seeking a non-animal source of this essential nutrient.
Although D2Z was designed to support immunity, its ingredients play key roles in the systems that regulate rest and recovery:
Vitamin D2 (from White Button Mushrooms)
Low levels of vitamin D have been associated with disrupted sleep patterns and poor sleep quality in several observational studies. By helping regulate circadian rhythms and supporting the brain’s production of melatonin (your sleep hormone), vitamin D2 may contribute to more restful sleep, especially for those who don’t get enough sun exposure.
Reishi Mushroom
Known for its adaptogenic properties, Reishi has a long history of traditional use in supporting relaxation and a sense of calm. It contains triterpenes that may promote parasympathetic nervous system activity (the "rest and digest" mode), helping to quiet the mind and prepare the body for sleep. Many Real Mushrooms customers report taking Reishi in the evening to unwind or improve restfulness.
Chelated Zinc
Zinc supports healthy nervous system function and plays a role in neurotransmitter signaling, which can influence mood and stress levels. Studies have also linked zinc status to better sleep quality and duration.
Natural ingredients don’t always flow smoothly through processing equipment and capsule manufacturers need to utilize other ingredients in order to fill capsules. It is common practise for encapsulation facilities to require the use of other ingredients.
We have worked closely with our encapsulation partners to make sure that only what is added is absolutely necessary to create the capsules.