38 reviews
Mushroom Immune Pet Chews
Pet Health†
Quantity
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Comprehensive immune support for pets in one tasty chew.
Veterinarian-formulated Mushroom Immune Pet Chews combine organic mushroom extracts with adaptogenic herbs and antioxidant-rich superfoods to strengthen your pet’s natural defenses.
With guaranteed beta-glucans in every serving, these grain-free chews are a convenient, palatable way to support immune balance, resilience, and overall vitality so your companion can stay strong and thrive through every stage of life.
Your pet’s immune system is the foundation of lifelong vitality, these chews make functional nutrition easy and enjoyable.
- Comprehensive Immune and Microbiome Support
- Whole Body Antioxidant Protection
- Adaptogenic Support for Stress and Balance
- Preconditioning for Strong Vaccine Response
- Longevity and Vitality Across Life Stages
- Support for Healthy Responses to Immune Challenges
- Cellular Protection and Detoxification Benefits
DOGS: Administer 1 soft chew for every 20lbs of body weight once daily or as directed by your veterinarian.
CATS: Administer 1/4 chew twice daily or as directed by your veterinarian.
Real Mushrooms products are always:
- Rated the #1 Mushroom brand by ConsumerLab
- Organic mushroom identity authenticated by Purity-IQ™
- Verified for active compounds, safety, & purity through third-party testing
- Free of grains, starches, and fillers
- Sourced from mushroom (fruiting bodies) only—never mycelium fermented grain
- Produced in a Good Manufacturing Practices (GMP)-compliant facility
This is our Real Mushrooms Guarantee: no shortcuts, no gimmicks—just real mushrooms.
100 Days
100 Days
Money-Back Guarantee
94,000+
94,000+
5 star reviews
50+ Years
50+ Years
Growing experience
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Real Pets. Real Results.†
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“My dog was found to have spots on her liver and spleen. Since I opted not to have her go thru a biopsy, she’s 12 years old, I decided to start the mushrooms. She’s doing so much better! It’s amazing. She is acting like she’s two again.”†
– Verified Customer
“Talk about a purr-fect surprise! I was a bit skeptical about finding something my picky furball would actually enjoy while also supporting his immune health. But lo and behold, these chews worked their magic! My cat not only gobbled them up but also gave me that "more, please!" look. I can't recommend this product enough – it's a win-win for both you and your furry friend."†
– Verified Customer
“I'm fostering a dog that has neurological issues and I give him Mushrooms Immune Pet Chews and it helps him a lot. He's more energetic and a happy boy. Thank you Real Mushrooms.”†
– Verified Customer
“I'm fostering a dog that has neurological issues and I give him Mushrooms Immune Pet Chews and it helps him a lot. He's more energetic and a happy boy. Thank you Real Mushrooms.”†
– Verified Customer
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Real Ingredients
5 Defenders® Mushroom Extract Blend (Organic)
A blend of five functional mushrooms (Reishi, Turkey Tail, Shiitake, Maitake mushrooms and Chaga extract powders) known for their immune-modulating benefits.
Boosts immune function, stabilizes mast cell membranes, has an anti-aging effect, and supports digestive health.
Ashwagandha Root (Organic) (KSM-66™)
Ashwagandha root is a traditional herb used in Ayurvedic health practices.
This ancient Ayurvedic herb supports stress reduction, energy, muscle function, immune health, and healthy aging in pets.
Astragalus Root
Astragalus root is a traditional herb derived from the Astragalus membranaceus plant, long used in Chinese wellness practices for immune and GI applications.
Astragalus root supports healthy immune function, anti-aging, and GI support in dogs and cats.
Acerola extract
Acerola extract is derived from the acerola cherry, a tropical fruit known for its rich content of vitamins, carotenoids, anthocyanidins and bioactive compounds such as ascorbic acid (vitamin C).
Acerola extract is a functional food containing many beneficial compounds that provide healthy support for cellular protection by scavenging tissue-damaging free radicals.
Olive Leaf Extract
Olive leaf extract is made from the leaves of the olive tree and is valued for its naturally occurring plant compounds.
Olive leaf contains a potent antioxidant called oleuropein, luteolin, apigenin, and several more antioxidant compounds that provide protection from cellular damage from reactive oxidative species.
Blueberry Powder
Blueberry powder is derived from dried blueberry fruits.
Blueberries are rich in naturally occurring antioxidants which when consumed regularly can provide cellular protection from oxidative stress that can support a healthy immune response.
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5-Time Winner
Best Mushroom Supplement Brand: ConsumerLab.com Survey
Trusted by wellness seekers and professionals alike, our mushroom supplements have earned the rating of Best Mushroom Supplement Products five years in a row by consumers in ConsumerLab.com Annual Supplement Survey.
†Ratings based on results of the 2025 ConsumerLab.com Survey of Supplement Users. More information.
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Real Quality
Real Mushrooms is built on 50+ years of mycological and mushroom-growing expertise. Our founder’s roots trace back to the beginning of the functional mushroom category in North America. Today, we continue to lead the industry in science-backed and effective mushroom supplements.
Purity, Potency, Transparency
Every batch of our supplements is lab-verified for purity. We test for unwanted fillers and various contaminants.
We ensure quality along the entire production process:
- Source: Organically grown mushrooms from trusted long-term partners
- Process: Extracted for bioavailability, lab-verified, and blended/packaged in the USA
- Testing: Each batch is tested for heavy metals, microbial contamination, pesticides & solvents
Nothing hidden. No marketing gimmicks. Just real ingredients, real science, and real results.
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Real Vet. Real Formula.
Dr. Robert Silver, DVM, MS
Chief Veterinary Officer Formulator
Dr. Robert Silver brings to the Real Mushrooms Science Team 40 years of practical clinical experience treating small and large animals with diet, acupuncture, nutraceuticals, botanicals, and medicinal mushrooms.
- Graduated from Colorado State's College of Veterinary Medicine in 1982.
- Established one of the first integrative vet clinics in the USA in Boulder, CO in 1993.
- Adjunct faculty member at several veterinary colleges.
- Published papers and books on the topic of alternative medicines for pet health.
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Real Mushrooms vs. Other Brands
Not all mushroom supplements are created equal. Real Mushrooms has set the standard for the most effective mushroom products because we have never compromised on quality. Here’s how Real Mushroom supplements compare with the other leading brands on the market.
Real Mushrooms
100% organic mushrooms
Guaranteed >30% beta-glucans
Hot water extracted or dual extracted
No starch · no fillers
Full disclosure of ingredients, sourcing, testing and extraction
Cost-effective for active compound concentration in every serving
50+ years mushroom cultivation expertise
Other Brands
Mycelium fermented grain (starch + fillers)
Typically low, often undisclosed
Improperly extracted or simply dried and ground
Commonly contains rice, oats or sorghum starch and/or maltodextrin
Vague or misleading marketing and unclear labeling
Very expensive for amount of active compounds actually present
Mislead customers with ambiguous labeling and filler-heavy products
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Take the guesswork out of your mushroom supplement. Start enjoying real results now.
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Nicole E. We have 3 small dogs; 2 with pretty significant allergies. We have run with the gambit in trying this and that for some relief. From Apoquel and Cytopoint, to creams, topicals, OTC allergy meds, and everything in between. Nothing was really giving them 100% relief and some seasons were still BAD! I came across an ad for medicinal mushrooms on FB and read some of the reviews and figured it couldn’t hurt to try. This is our 2nd month on these pills and while I can’t say with certainty that these are the holy grail for dogs, I can definitely tell their itching is SIGNIFICANTLY LESS! They won’t take the pills outright. One will take it broken up in his food and the other one will take it halved in sliced turkey (but not in his food) I will do whatever to find them some relief so for now we are staying on them! (It’s been at least 2 months since they’ve gotten a Cytopoint shot and as long as they continue to be good on these pills, I will continue to get them and not the shots)
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Karen S. I have 4 Labrador Retrievers. 3 which are Seniors. I go without to make sure they have the best fresh food and supplements.
I have used Real Mushroom brand for myself and my pets for many years. My oldest Labrador is 13 yrs old and still plays like a puppy.
I trust and recommend this brand over all others!
K Simmons
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Maggie a.K. My 14 year old American Fox Hound is doing so much better in the 3 short weeks she's been taking this supplement! She has a whole lot more energy, tail wags and hound sass than she has for the last 5 years. She was in the typical elderly decline of old dogs. Having a harder time getting up the stairs, napping a lot, disinterested in playing, getting fatty lumps. Three weeks of this supplement and she's like she was when she was 7! Absolutely grateful to have found this and to have my sassy hound back! Thank you for your amazing product ❤️ I will be a lifetime customer!
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RWP I've been giving my Golden Retriever the immune chews ever since they appeared on the market. He love them. Goldens are prone to a number of health issues (including tumors), but at 10 years old, he has no sign of any problems.
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Gabriela R. My dog has severe allergies, I decided to give real mushrooms a chance and see how it went. I have Tried many different immune support products with him and unfortunately they work for a couple of weeks only. Real mushrooms has been working great. He had all his belly and back covered in red bumps. Since we started this product all of it has gone away. He is no longer itching all the time. He is more playful and has more energy!! This product is a blessing!!
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Frequently Asked Questions
All our mushroom extracts are from the leading supplier of organic mushroom extracts: Nammex. They have over 40 years of mushroom growing experience and were one of the first companies to bring organic functional mushroom extracts to North America.
Their ingredients go through rigorous quality control and are tested twice for heavy metals, agricultural chemicals and microbial contamination to ensure they meet all standards for dietary supplements of this nature. All of their extracts are made from certified organic mushrooms (fruiting bodies), organically grown or wildcrafted from deep within mountain regions of China.
Mushrooms used for dietary supplements are seldom grown in North America since they are too expensive. China is the leading supplier of mushrooms worldwide and supplies over 90% of the world’s mushrooms.
It has a rich history of mushroom use as both food and medicine and is the birthplace of mushroom cultivation, with shiitake being farmed in the early 1200s. China is one of the only places in the world where you can get 100% organic mushroom (fruiting body) extracts that can be sold at an affordable price.
It is extremely important to distinguish the difference between mushrooms and mycelium.
Mushrooms are the "fruit" and reproductive stage of these organisms, while the mycelium is the root system or "body" of the fungus.
Mushrooms contain much higher levels of active compounds like beta-glucans, and there is a large body of research on them. They have also been consumed for thousands of years as food, and many health benefits have been shown from just mushroom consumption.
Mycelium is commonly grown on a grain substrate, and this grain cannot be separated from the mycelium, so much of the final product is actually grain with no mushrooms present. This shows up in high amounts of starch and low amounts of active compounds like beta-glucans.
For these reasons, Real Mushrooms® only utilizes mushrooms in all of its products, with verified levels of important active compounds like beta-glucans, and is always guarded against starchy fillers like grain.
NSF certification ensures the product is manufactured under strict cleanliness, safety, and quality control guidelines. This means you can trust that Daily Dawg Powder meets the highest standards for pet supplements.
Mushroom Immune Chews support the microbiome and healthy immune system function with a blend of five powerful mushroom extracts, plant-based antioxidants, adaptogens, and herbal tonics.
Dogs: Give 1 soft chew for every 20 pounds of body weight once daily, or as directed by your veterinarian.
Cats: Give 1⁄4 chew twice daily, or as directed by your veterinarian.
They can be given daily as part of a proactive wellness routine.
Yes, Immune Chews are safe for both dogs and cats.
There are no reported negative interactions between mushrooms and common pet supplements or medications. Still, we always suggest checking with your veterinarian before starting any new supplement routine.
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