What is the Cordyceps Zombie Fungus?

What is the Cordyceps Zombie Fungus? cover
Written by Skye Chilton - Updated: March 14, 2025
A before and after image of caterpillar infected by the cordyceps "zombie fungus"
Cordyceps is known to infect ants and other insects, including caterpillars.

The Cordyceps fungus, also known as the "zombie fungus," is one of nature's most remarkable creations. Famous for its ability to infect and control the behavior of insects, Cordyceps offers a glimpse into the extraordinary complexities of the natural world.

Beyond its eerie life cycle, the fungus has made a name for itself in traditional medicine and modern supplements, celebrated for its purported health benefits.

Let’s explore how this fascinating organism operates, its role in ecosystems, and its growing use in the wellness industry.

In This Article

  1. Why Is It Called a Zombie Fungus?
  2. Spotlight on Prominent Cordyceps Species
  3. Ophiocordyceps sinensis
  4. Cordyceps militaris
  5. Ophiocordyceps unilateralis
  6. How Does It Turn Insects into "Zombies"?
  7. Could Cordyceps Ever Infect Humans?
  8. Cordyceps and Modern Health Applications
  9. A Fungus of Many Facets

Why Is It Called a Zombie Fungus?

Cordyceps is a genus of fungi comprising over 400 species [1], uniquely characterized by their parasitic ability to hijack the bodies of insects. These fungal species infiltrate their hosts—such as carpenter ants, caterpillars, or beetles—by attaching fungal spores to the insect’s exoskeleton and penetrating its body.

Once inside, this parasitic fungus commandeers the host’s central nervous system, eventually steering its behavior. In a remarkable feat of biological control, the infected insect is driven to climb to an elevated position, ideal for spore dispersal when the fungus later emerges.

This chilling survival strategy has made Cordyceps a subject of both scientific fascination and ecological importance. By regulating insect populations [2], the fungus prevents overpopulation that could destabilize ecosystems and overconsume resources.

Interestingly, the significance of Cordyceps extends beyond its macabre life cycle. In Himalayan cultures, some species have been prized for centuries as natural remedies for enhancing vitality and endurance. Today, the fungus is not only a marvel of nature but also a valuable resource in traditional medicine and modern health supplements.

Spotlight on Prominent Cordyceps Species

With hundreds of identified species of Cordyceps, at least 35 are recognized for their potential health benefits and medicinal properties. Among these, a few stand out for their unique biology and uses. Let’s take a closer look.

Ophiocordyceps sinensis

Native to the Tibetan Plateau, this unique fungus has been traditionally used in herbal practices. Known as the 'caterpillar fungus' due to its natural symbiosis with caterpillars, it has been valued for its role in supporting vitality, endurance, and overall well-being.

Cordyceps militaris

cordyceps powder in a pouch and a hand holding a teaspoon of cordyceps mushrooms
Real Mushrooms Cordyceps Powder can be mixed into teas and used in culinary applications for everyday health support.

Unlike Ophiocordyceps sinensis, Cordyceps militaris can be sustainably cultivated without reliance on insect hosts [3]. Its vibrant orange fruiting body is often featured in functional mushroom supplements, offering a cost-effective and eco-friendly alternative.

shop cordyceps mushrooms

Ophiocordyceps unilateralis

Also known as the “zombie ant fungus,” this species may produce bioactive compounds like red naphthoquinones with potential anti-malarial properties [4]. Famous for its mind-control abilities, it compels the infected ants to climb vegetation for optimal spore dispersal.

Beyond its chilling behavior, this fungus showcases the ecological significance [5] and biotechnological potential [6] of Cordyceps.

How Does It Turn Insects into "Zombies"?

The zombie-like behavior Cordyceps triggers in its hosts is a masterstroke of evolutionary adaptation. By releasing targeted enzymes and chemical compounds, the fungus overrides the insect's behavior.

Ophiocordyceps unilateralis fungus infects an ant’s behavior, directing the infected ant to climb a plant stalk and clamp onto it in a “death grip” [7] This ensures the fungus's fruiting body will grow in an advantageous location for fungal spore dispersal.

Over time, the fungus consumes the insect from the inside, using it as a living incubator before completing its reproductive cycle. The methodical precision of this process has fascinated scientists and inspired popular media, from novels like “The Girl With All the Gifts” to the video game (and TV series) “The Last of Us.

Could Cordyceps Ever Infect Humans?

No, Cordyceps cannot control or infect humans or the human body. Its mechanisms for parasitism are strictly species-specific, finely tuned to the biology of its insect hosts over millions of years.

Humans lack the biochemical pathways that the parasitic fungus uses to infiltrate and manipulate insects. So, rest easy—there’s no real-life zombie apocalypse in the making.

This species-specific adaptation is precisely what fascinates scientists. By studying how Cordyceps targets insects so effectively, researchers hope to uncover new insights into parasitism, fungal biology, and potentially even functional applications.

Cordyceps and Modern Health Applications

woman wearing face mask and gloves holding cordyceps mushrooms
Cordyceps is grown and harvested at our cultivation farms in China.

In recent years, Cordyceps has enjoyed a surge in popularity as a key ingredient in health supplements, prized for its potential benefits like supporting health energy levels, overall respiratory health, and supporting immune function. These supplements are commonly derived from other species like Ophiocordyceps sinensis and Cordyceps militaris.

Cordyceps is used by some to support energy levels and endurance, particularly among active individuals. This property makes it particularly popular among athletes [8] and those looking to increase respiratory capacity [9]. Cordyceps is used by some to support energy levels and endurance, particularly among active individuals.

When in doubt, boost your diet with a product that uses scientifically tested production methods that ensure Cordyceps extracts retain maximum potency. These supplements are often derived from the mushroom (fruiting body of the fungus), where most of its bioactive compounds are concentrated, rather than from mycelium grown on grain.

Incorporating Cordyceps into Wellness Routines

woman holding a cordyceps mushroom supplement bottle and its capsules on her other hand
Real Mushrooms cordyceps capsules are the ideal way to add Cordyceps to your everyday wellness routine.

Cordyceps mushrooms are often available as powders, capsules, and tinctures. Some of the most noted benefits include:

  • Energy and Endurance: Cordyceps supports ATP production [10], enhancing cellular energy levels.
  • Respiratory Health: By promoting oxygen efficiency, it may improve lung function.
  • Immune Support: Thanks to bioactive compounds, Cordyceps aids natural immune responses.

When selecting supplements, focus on products that prioritize the use of high-quality ingredients to ensure effectiveness. This means avoiding products that use myceliated biomass, as that is simply the root structure of the mushroom and the grain it is grown on. Such products are low in bioactive compound concentration and high in starch from the grain.

A Fungus of Many Facets

Cordyceps is more than just a parasite that turns other insects into improbable climbers. It is a vital part of its ecosystem, helping regulate populations and maintain biodiversity. For humans, it serves as a bridge between ancient traditions and modern wellness, offering a range of potential health benefits.

By understanding its lifecycle, ecological importance, and functional applications, we can appreciate this strange and spectacular organism on a deeper level.

shop cordyceps

Related Articles

References

  1. Sung, G. H., Hywel-Jones, N. L., Sung, J. M., Luangsa-Ard, J. J., Shrestha, B., & Spatafora, J. W. (2007). Phylogenetic classification of Cordyceps and the clavicipitaceous fungi. Studies in mycology, 57, 5–59. https://doi.org/10.3114/sim.2007.57.01
  2. Lovett, B., & St Leger, R. J. (2017). The insect pathogens. Microbiology Spectrum, 5(2). https://doi.org/10.1128/microbiolspec.funk-0001-2016
  3. Nguyen, N. Q., Nguyen, V. T., Nguyen, M. T., Thanh, L. V., Phuong, T. T. M., & Duong, D. C. (2020). Screening of extraction conditions by Plackett–Burman design for extraction of Cordyceps militaris Cordycipitaceae. IOP Conference Series Materials Science and Engineering, 991(1), 012017. https://doi.org/10.1088/1757-899x/991/1/012017
  4. Wongsa, P., Tasanatai, K., Watts, P., & Hywel-Jones, N. (2005). Isolation and in vitro cultivation of the insect pathogenic fungus Cordyceps unilateralis. Mycological Research, 109(8), 936–940. https://doi.org/10.1017/s0953756205003321
  5. Evans, H., Araújo, J., Halfeld, V., & Hughes, D. (2017). Epitypification and re-description of the zombie-ant fungus, Ophiocordyceps unilateralis (Ophiocordycipitaceae). Fungal Systematics and Evolution, 1(1), 13–22. https://doi.org/10.3114/fuse.2018.01.02
  6. Lu, Y., Tang, D., Liu, Z., Zhao, J., Chen, Y., Ma, J., Luo, L., & Yu, H. (2024b). Genomic comparative analysis of Ophiocordyceps unilateralis sensu lato. Frontiers in Microbiology, 15. https://doi.org/10.3389/fmicb.2024.1293077
  7. Hughes, D. P., Andersen, S. B., Hywel-Jones, N. L., Himaman, W., Billen, J., & Boomsma, J. J. (2011). Behavioral mechanisms and morphological symptoms of zombie ants dying from fungal infection. BMC Ecology, 11(1), 13. https://doi.org/10.1186/1472-6785-11-13
  8. Nakamura, A., Shinozaki, E., Suzuki, Y., Santa, K., Kumazawa, Y., Kobayashi, F., Nagaoka, I., & Koikawa, N. (2024). Effect of the Administration of Cordyceps militaris Mycelium Extract on Blood Markers for Anemia in Long-Distance Runners. Nutrients, 16(12), 1835. https://doi.org/10.3390/nu16121835
  9. Chen, M., Cheung, F. W., Chan, M. H., Hui, P. K., Ip, S. P., Ling, Y. H., Che, C. T., & Liu, W. K. (2012). Protective roles of Cordyceps on lung fibrosis in cellular and rat models. Journal of ethnopharmacology, 143(2), 448–454. https://doi.org/10.1016/j.jep.2012.06.033
  10. Choi, E., Oh, J., & Sung, G. H. (2020). Beneficial Effect of Cordyceps militaris on Exercise Performance via Promoting Cellular Energy Production. Mycobiology, 48(6), 512–517. https://doi.org/10.1080/12298093.2020.1831135

.
Skye is the founder of Real Mushrooms. Read more about his story into medicinal mushrooms here. When he’s not spreading the word of Real Mushrooms, he enjoys mushroom foraging, bouldering, cooking, gardening and hiking.

Disclaimer: The information or products mentioned in this article are provided as information resources only, and are not to be used or relied on to diagnose, treat, cure, or prevent any disease. This information does not create any patient-doctor relationship, and should not be used as a substitute for professional diagnosis and treatment. The information is intended for health care professionals only. The statements made in this article have not been evaluated by the Food and Drug Administration. Any products mentioned are not intended to diagnose, treat, cure, or prevent any disease. The information in this article is intended for educational purposes. The information is not intended to replace medical advice offered by licensed medical physicians. Please consult your doctor or health practitioner for any medical advice.

chevron-down