Best Time To Take Cordyceps Mushrooms

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Written by Skye Chilton - Updated: April 17, 2025

Cordyceps mushrooms, a type of functional mushroom, have been used in traditional Chinese medicine for centuries. Known for their potential health benefits, including supporting healthy energy levels, athletic performance, and immune function, these functional mushrooms have gained popularity as natural supplements.

Understanding the optimal timing for consuming Cordyceps can maximize their efficacy and ensure users receive the full range of benefits they offer.

This article explores when best to take Cordyceps mushrooms, considering various factors such as daily routines, health goals, and potential interactions with other substances.

In this Article

What Are Cordyceps Mushrooms?

Cordyceps mushrooms are a genus of parasitic fungi containing several bioactive components, including cordycepin, adenosine, and polysaccharides, which are believed to contribute to their health-supporting properties [1].

The two most well-known species, Cordyceps sinensis, and Cordyceps militaris, are widely used in traditional and modern wellness practices.

Cordyceps have been traditionally used in wellness practices to support overall vitality and energy levels, and have been valued in traditional medicine for their role in promoting general well-being [2].

In modern times, Cordyceps mushroom supplements are widely available in various forms, including capsules, powders, and extracts.

Many high-quality supplements use the fruiting body of the mushroom for maximum potency, and some are included in functional mushroom blends designed to support overall wellness.

When Should You Take Cordyceps Mushrooms?

image of the pros for taking cordyceps mushroom at a certain time in a day

Should Cordyceps Be Taken in the Morning or Evening?

The optimal time to take Cordyceps mushrooms can vary depending on individual goals and lifestyle. Many individuals choose to take Cordyceps in the morning to capitalize on its energy-supporting properties throughout the day.

Taking Cordyceps in the morning may help to increase stamina and endurance, making it a popular choice for athletes or those with demanding daily schedules [3]. Some people even add Cordyceps powder to their morning coffee for an extra energy boost.

Conversely, some individuals may prefer to take Cordyceps in the evening, particularly if their primary goal is to support recovery and relaxation.

While Cordyceps is not typically associated with sedative effects, its adaptogenic properties may help the body adapt to stress and support a balanced state, which can be beneficial in the evening as the body prepares for rest.

The timing of Cordyceps supplements can impact absorption and overall effectiveness. Taking them on an empty stomach may enhance nutrient uptake, while consuming them with food can help prevent digestive discomfort. Since individual responses vary, experimenting with timing is key to finding what works best.

For those seeking a natural energy boost, taking Cordyceps in the morning, perhaps in a mushroom coffee blend, can help promote sustained vitality throughout the day. Alternatively, those using functional mushrooms for antioxidant properties or recovery may prefer taking them in the evening.

Ultimately, the ideal timing depends on personal energy levels, daily routine, and health goals, allowing you to maximize the benefits of Cordyceps supplementation.

How Does Timing Affect the Benefits of Cordyceps?

The timing of Cordyceps mushroom intake can significantly influence its benefits, as the body's natural rhythms and metabolic processes vary throughout the day. Taking Cordyceps at specific times may enhance these effects by aligning with the body's circadian rhythms.

In the morning, Cordyceps may be particularly effective for boosting energy levels and enhancing mental clarity. This is due to its potential to increase ATP production, which is crucial for cellular energy [4].

By taking Cordyceps in the morning, individuals may experience improved stamina and focus throughout the day, making it a popular choice for those seeking to enhance productivity and physical performance.

Conversely, taking Cordyceps in the evening may support relaxation and recovery processes. While Cordyceps is not typically associated with sedative effects, its role in reducing oxidative stress and supporting immune function can contribute to overall well-being and recovery during sleep.

In a laboratory study, extracts of Cordyceps militaris were observed to support healthy immune function and reduce oxidative stress in cell cultures. While promising, more research is needed to understand the implications for human health [5].

Choosing the right time to take cordyceps can also impact its adaptogenic benefits. Adaptogens work by supporting the body's stress response, and taking Cordyceps at times of anticipated stress may enhance its effectiveness [6].

For example, consuming Cordyceps supplements before a stressful event or after a physically demanding activity can help the body adapt more efficiently, potentially reducing the negative impacts of stress.

Highlight: The timing of Cordyceps intake can influence its benefits by aligning with the body's natural rhythms. Taking it in the morning may boost energy and focus, while evening consumption may aid recovery and reduce oxidative stress, enhancing overall well-being.

How Do Cordyceps Mushrooms Work in the Body?

How can cordyceps support overall health
Cordyceps mushrooms support healthy energy and stamina levels, but may also support relaxation and immune health

Cordyceps mushrooms are renowned for their unique bioactive compounds, which contribute to their wide array of health benefits.

The primary active compounds found in Cordyceps include cordycepin, adenosine, polysaccharides, and sterols. Each of these compounds plays a distinct role in the physiological effects attributed to Cordyceps [1].

Cordycepin, also known as 3'-deoxyadenosine, is a nucleoside analogue that has been extensively studied for its potential supportive properties. It is believed to exert anti-inflammatory, anti-tumor, and immune-supporting effects.

Cordycepin's structure is similar to that of adenosine, allowing it to interfere with cellular processes such as DNA and RNA synthesis, which may contribute to its anti-malignant cell growth properties.

Polysaccharides present in Cordyceps are complex carbohydrates that have been shown to possess immunostimulatory properties.

These compounds can enhance the activity of various immune cells, such as macrophages and natural killer cells, thereby bolstering the body's defense mechanisms against infections and diseases.

Additionally, Cordyceps polysaccharides have been associated with antioxidant activity, which helps in fighting oxidative stress and protecting cells from damage.

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Can Cordyceps Be Taken With Other Supplements or Medications?

Cordyceps mushrooms, like many dietary supplements, may interact with certain medications, potentially altering their effects or leading to adverse reactions.

It is crucial for individuals using Cordyceps supplements to be aware of these potential interactions and consult with healthcare professionals before combining them with prescription drugs.

One of the primary concerns is the potential interaction between Cordyceps supplements and immunosuppressive medications.

Cordyceps is often used to support normal immune system function. However, individuals on immunosuppressive therapy should consult healthcare professionals before use.

Additionally, Cordyceps may affect blood sugar levels, which could interfere with the efficacy of antidiabetic medications [7].

Individuals taking insulin or oral hypoglycemic agents should monitor their blood sugar levels closely and consult their healthcare provider to adjust their medication dosage if necessary.

There is also a potential for interaction with anticoagulants or antiplatelet drugs. Cordyceps may have blood-thinning effects, which could enhance the action of medications such as warfarin, aspirin, or clopidogrel, increasing the risk of bleeding [8].

What Are the Recommended Dosages for Cordyceps?

cordyceps powder extract supplement
Cordyceps can be mixed into tea, coffee, or a smoothie on a daily basis to support overall health.

The ideal cordyceps dosage depends on several factors, including the form of cordyceps consumption, individual health status, and specific wellness goals. Cordyceps militaris can be available in various supplement forms, such as capsules, powders, and extracts, each with unique dosage guidelines.

Cordyceps supplements are often offered in doses ranging from 500 to 1,500 milligrams per day, depending on product formulation and intended use. Consult a healthcare provider to determine the appropriate amount for your needs. This dosage is typically divided into two or three smaller doses throughout the day to enhance absorption and maintain consistent levels in the bloodstream.

It is important to note that the dosage may need to be adjusted based on individual health conditions and responses.

For instance, individuals seeking to improve athletic performance might require a higher dosage within the recommended range, while those using Cordyceps for general wellness and overall health might opt for a lower dosage [3] [9].

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What Are the Common Side Effects of Cordyceps?

Cordyceps mushrooms, while generally considered safe for most individuals, may cause certain side effects in some users.

These side effects are typically mild and may vary depending on the individual's health status, dosage, and duration of use. Common side effects associated with Cordyceps include:

  • Digestive Issues: Some individuals may experience gastrointestinal discomfort, such as nausea, diarrhea, or an upset stomach.
  • Dry Mouth: A sensation of dry mouth has been reported by some users.
  • Drowsiness: Although Cordyceps is often used for its energy-supporting properties, some individuals may experience drowsiness or fatigue.
  • Allergic Reactions: In rare cases, individuals may experience allergic reactions to Cordyceps.
  • Hormonal Effects: Some preliminary research suggests that Cordyceps may interact with hormonal pathways, though more studies are needed.

The occurrence of side effects can be influenced by the quality and purity of the Cordyceps product being used.

When incorporating Cordyceps supplements into your routine, choosing high-quality supplements from reputable sources is essential to minimize the risk of adverse effects.

Additionally, lifestyle factors, such as diet and overall health, can also impact how your body responds to Cordyceps.

Who Should Avoid Taking Cordyceps Mushrooms?

While Cordyceps mushrooms offer various health benefits, certain groups should avoid their use or seek medical advice to ensure safety. Individuals with autoimmune diseases, such as lupus, multiple sclerosis, or rheumatoid arthritis, may need to avoid Cordyceps, as it can potentially stimulate the immune system and exacerbate these conditions.

Pregnant or breastfeeding women are generally advised to avoid Cordyceps due to insufficient research on its safety in these populations. It is crucial for these individuals to consult with a healthcare provider before considering Cordyceps supplementation.

Individuals with known allergies to fungi or mold should avoid Cordyceps, as it may trigger allergic reactions. Those undergoing surgery should also refrain from using Cordyceps at least two weeks prior to the procedure, as it may affect blood clotting.

Optimize Your Cordyceps Intake

Rooted in Traditional Chinese Medicine, Cordyceps mushrooms are widely available as Cordyceps capsules, powders, and extracts, making them an easy addition to daily wellness routines.

The optimal health benefits of Cordyceps depend on factors like timing, dosage, and individual health goals. While some may prefer taking them in the morning for sustained energy, others integrate them with other supplements based on their needs.

Understanding the active compounds, potential interactions, and recommended dosages ensures you get the most out of your Cordyceps regimen.

Ready to experience the optimal benefits of Cordyceps mushrooms? Explore Real Mushrooms' range of organic, high-quality Cordyceps products today. Dive into a world of enhanced vitality and well-being—don't wait to transform your health journey!

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References

  1. Qu, S., Li, S., Li, D., & Zhao, P. (2022). Metabolites and Their Bioactivities from the Genus Cordyceps. Microorganisms, 10(8), 1489. https://doi.org/10.3390/microorganisms10081489
  2. Lin, B. & and Li, S. (n.d.). Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition. Retrieved from: https://www.ncbi.nlm.nih.gov/books/NBK92758/#__NBK92758_dtls__
  3. Hirsch, K. R., Smith-Ryan, A. E., Roelofs, E. J., Trexler, E. T., & Mock, M. G. (2016c). Cordyceps militaris Improves Tolerance to High-Intensity Exercise After Acute and Chronic Supplementation. Journal of Dietary Supplements, 14(1), 42–53. https://doi.org/10.1080/19390211.2016.1203386
  4. Choi, E., Oh, J., & Sung, G. (2020). Beneficial Effect of Cordyceps militaris on Exercise Performance via Promoting Cellular Energy Production. Mycobiology, 48(6), 512–517. https://doi.org/10.1080/12298093.2020.1831135
  5. Lan, Y., Lu, Y., Wu, J., Lee, H., Srinophakun, P., Canko, G. N., Chiu, C., & Wang, H. D. (2022). Cordyceps militaris Reduces Oxidative Stress and Regulates Immune T Cells to Inhibit Metastatic Melanoma Invasion. Antioxidants, 11(8), 1502. https://doi.org/10.3390/antiox11081502
  6. What are adaptogens and the possible benefits of taking them? | UCLA Fielding. (n.d.). https://ph.ucla.edu/news-events/news/what-are-adaptogens-and-possible-benefits-taking-them
  7. Dong, Y., Jing, T., Meng, Q., Liu, C., Hu, S., Ma, Y., Liu, Y., Lu, J., Cheng, Y., Wang, D., & Teng, L. (2014b). Studies on the antidiabetic activities ofCordyceps militarisExtract in Diet-Streptozotocin-Induced diabetic Sprague-Dawley rats. BioMed Research International, 2014, 1–11. https://doi.org/10.1155/2014/160980
  8. Cordyceps is a killer fungi with potential health benefits. (2024, July 8). Cleveland Clinic. https://health.clevelandclinic.org/cordyceps-benefits
  9. Dubhashi, S., Sinha, S., Dwivedi, S., Ghanekar, J., Kadam, S., Samant, P., Datta, V., Singh, S., Chaudry, I. H., Gurmet, P., Kelkar, H., Mishra, R., Galwankar, S., & Agrawal, A. (2023). Early Trends to Show the Efficacy of Cordyceps militaris in Mild to Moderate COVID Inflammation. Cureus. https://doi.org/10.7759/cureus.43731

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Skye is the founder of Real Mushrooms. Read more about his story into medicinal mushrooms here. When he’s not spreading the word of Real Mushrooms, he enjoys mushroom foraging, bouldering, cooking, gardening and hiking.

Disclaimer: The information or products mentioned in this article are provided as information resources only, and are not to be used or relied on to diagnose, treat, cure, or prevent any disease. This information does not create any patient-doctor relationship, and should not be used as a substitute for professional diagnosis and treatment. The information is intended for health care professionals only. The statements made in this article have not been evaluated by the Food and Drug Administration. Any products mentioned are not intended to diagnose, treat, cure, or prevent any disease. The information in this article is intended for educational purposes. The information is not intended to replace medical advice offered by licensed medical physicians. Please consult your doctor or health practitioner for any medical advice.

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